Substances in database
Example sheet
Database access
Last subscription

EFSA review of Maximum Residue Limits for halquinol in pig tissues as set by JECFA

Undefined

The European Commission requested the European Food Safety Authority (EFSA) to review the evaluation of halquinol by the 85th and 88th meetings of the Joint FAO/WHO Expert Committee on Food Additives (JECFA) and to assess any other relevant scientific information in order to establish whether there is ground for any food safety concerns about the maximum residues levels (MRLs) recommended by JECFA. In several countries halquinol is used as a veterinary drug in pigs and poultry to enhance growth performance while this is prohibited in the European Union. JECFA derived an Acceptable daily intake (ADI) of 0‐0.2 mg/kg body weight, based on histopathological changes associated with an increase in mean absolute and relative kidney weights seen in a 1‐year chronic toxicity study conducted in rats and has recommended MRLs for halquinol of 500, 9000, 40 and 350 μg/kg in pigs liver, kidney, muscle and skin+fat, respectively. Overall, EFSA considers that the MRLs for halquinol proposed by JECFA are sufficiently low to ensure the safety of European consumers when exposed to foodstuffs from halquinol treated pigs. However, due to some limitations and uncertainties in the toxicological database available, EFSA is not in the position to confirm the ADI of 0‐0.2 mg/kg bw, as set by JECFA.

Last Tweets

06/06/2016 - 11:11
Nuovo componente inserito: Simmondsia Chinensis (Jojoba) Seed Oil https://t.co/mGvGLRQ05k
29/05/2016 - 10:04
Nuovo componente inserito: Linum Usitatissimum seed oil Error
27/05/2016 - 16:38
Nuovo componente inserito: Soybean oil https://t.co/9prxB7xyiu

NOAEL-crew

Project coordinator

Toxicological datasheet creation

Content revision

Website Administration

Subscriptions & Contacts

To get more info about the NOAEL project, go to FAQ section or contact Roberto Narducci at this address:
 
infoATnoaelproject.it or robymagnoATgmail.com
 
For info about subscription costs click the following link or contact Federica Cambiganu:
 
federica.cambiganuATpin.unifi.it
+390574602511
PIN s.c.r.l. - Piazza Giovanni Ciardi 25, 59100 - Prato