Serena

Name and Surname:

Serena Di Pirro

Email:

serena.dipirro@gmail.com

Role in NOAEL-project:

Content revision

Toxicological datasheet creation

Curruculum vitae:

CV SerenaDiPirroNOAEL-english.pdf

Education and training:

Date:

February, 2014

Title of qualification awarded:

Pharmacist

Thesis title:

“Characterization of Schwann cells murine model in hyperglycemic condition and calpain-2 down-regulation by siRNA”

Main projects:

Preclinical research devoted to the study of biomolecular mechanisms underlying neuropathy with particular reference to the possible therapeutic developments.

Organization providing education:

University of Florence

Personal skills and expertise:

Preparation of galenic formulation (cream, capsules, powders...);

Cultivation of immortalised cell lines;

Molecular biology techniques: knock-down by siRNA ;

Application of tests for the determination of biomarkers of oxidative stress on animal samples (TBARS, superoxide anion, caspase-3…);

Immunocytochemistry and immunohistochemistry;

Use of microtome and cryostat ;

Handling of laboratory animals and practice with the main routes of administration (oral gavage, intravenous injection);

Behavioral evaluation of the threshold painful by the main assays for the measurement of analgesic response and hyperalgesia and allodynia induced by physical and chemical stimuli.