ItalyName and Surname:
Serena Di Pirro
Email:
serena.dipirro@gmail.com
Role in NOAEL-project:
Content revision
Toxicological datasheet creation
Curruculum vitae:
Education and training:
Date:
February, 2014
Title of qualification awarded:
Pharmacist
Thesis title:
“Characterization of Schwann cells murine model in hyperglycemic condition and calpain-2 down-regulation by siRNA”
Main projects:
Preclinical research devoted to the study of biomolecular mechanisms underlying neuropathy with particular reference to the possible therapeutic developments.
Organization providing education:
Personal skills and expertise:
Preparation of galenic formulation (cream, capsules, powders...);
Cultivation of immortalised cell lines;
Molecular biology techniques: knock-down by siRNA ;
Application of tests for the determination of biomarkers of oxidative stress on animal samples (TBARS, superoxide anion, caspase-3…);
Immunocytochemistry and immunohistochemistry;
Use of microtome and cryostat ;
Handling of laboratory animals and practice with the main routes of administration (oral gavage, intravenous injection);
Behavioral evaluation of the threshold painful by the main assays for the measurement of analgesic response and hyperalgesia and allodynia induced by physical and chemical stimuli.
