Sostanze in database
Scheda d'esempio
Accesso al database
Ultima azienda iscritta

Safety evaluation of the food enzyme endo‐1,4‐β‐xylanase from the genetically modified Bacillus subtilis strain DP‐Ezd31

Undefined

The food enzyme endo‐1,4‐β‐xylanase (4‐β‐d‐xylan xylanohydrolase; EC 3.2.1.8) is produced with a genetically modified Bacillus subtilis strain DP‐Ezd31 by Danisco US Inc. The production strain of the food enzyme contains multiple copies of a known antimicrobial resistance gene. However, based on the absence of viable cells and DNA from the production organism in the food enzyme, this is not considered to be a safety concern. The production strain was not shown to meet the criteria for Qualified Presumption of Safety (QPS) approach to safety assessment. The substitute studies provided were not considered suitable for the toxicological assessment of this food enzyme. A search for similarity of the amino acid sequence to known allergens was made and no match was found. The Panel considered that, under the intended conditions of use, the risk of allergic sensitisation and elicitation reactions by dietary exposure cannot be excluded, but the likelihood for this to occur is considered to be low. In the absence of suitable toxicological studies, the Panel cannot conclude on the safety of the food enzyme.

Ultimi Tweets

06/06/2016 - 11:11
Nuovo componente inserito: Simmondsia Chinensis (Jojoba) Seed Oil https://t.co/mGvGLRQ05k
29/05/2016 - 10:04
Nuovo componente inserito: Linum Usitatissimum seed oil Error
27/05/2016 - 16:38
Nuovo componente inserito: Soybean oil https://t.co/9prxB7xyiu

NOAEL-crew

Coordinatore progetto

Inserimento ingredienti cosmetici

Revisione contenuti

Amministrazione del sito

Adesioni e contatti

Per informazioni tecniche sul progetto andare alla sezione FAQ o contattare Roberto Narducci:
 
infoATnoaelproject.it o robymagnoATgmail.com
 
Per informazioni riguardo i costi e le modalità di adesione contattare Federica Cambiganu:
 
federica.cambiganuATpin.unifi.it
 +390574602511
PIN s.c.r.l. - Piazza Giovanni Ciardi 25, 59100 - Prato